GeneTex

  • Country / Location Selection

United States (US)

PARP2 antibody

Anti-PARP2 antibody used in Western Blot (WB). GTX01558
Anti-PARP2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX01558

Cat. No. GTX01558

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF

Reactivity

 Human, Mouse
Package
100 μl ($399)
See all PARP2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:1000
ICC/IF 1:100-1:500
Not tested in other applications.

Calculated MW

66 kDa. ( Note )

Predict Reactivity

Zebrafish, Rabbit, Sheep, Bovine, Dog, Pig, Horse(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 150mM NaCl, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthesized peptide derived from human PARP2, corresponding to a region within the internal amino acids.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

poly(ADP-ribose) polymerase 2 , ADPRT2 , ADPRTL2 , ADPRTL3 , ARTD2 , PARP-2 , pADPRT-2

Cellular Localization

Nucleus

Background

This gene encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-PARP2 antibody used in Western Blot (WB). GTX01558

GTX01558 WB Image

WB analysis of 3T3 cell lysate using GTX01558 PARP2 Antibody. The lane on the left was treated with blocking peptide.

Anti-PARP2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX01558

GTX01558 ICC/IF Image

ICC/IF analysis of PFA-fixed K562 cells using GTX01558 PARP2 Antibody.
Permeabilization : 0.1% Triton X-100
Dilution : 1:200

REFERENCE

Application Reference

Zhao ML et al. DNA Repair (Amst) 2023; 126 : 103486 Temporal recruitment of base excision DNA repair factors in living cells in response to different micro-irradiation DNA damage protocols.
Submit a Reference

REVIEW

There are currently no reviews for PARP2 antibody (GTX01558). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399