Form
Liquid
Buffer
Serum
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Purification
Serum
Conjugation
Unconjugated
RRID
AB_374147
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
Background
Poly(ADP-ribose) polymerase 1, (PARP-1) and poly(ADP-ribose) polymerase 2 (PARP-2) catalyze the formation of poly(ADP-ribose) polymers in a DNA-dependent manner. PARP-2 displays automodification properties similar to PARP-1. These act by poly(ADP-ribosylation), which is a post-translational modification of nuclear proteins in response to DNA damage that activates the base excision repair machinery.
Research Area