GeneTex
United States (US)

PATJ antibody, N-term

GTX28225_414_IHC-P_18121410_200.jpg

Cat No. GTX28225

Host Goat
Clonality Polyclonal
Isotype IgG
Application IHC-P
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 3-6μg/ml

Note :

IHC-P
Human Testis shows strong staining of spermatids.

Not tested in other applications.

Calculated MW

196 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX28225-PEP).

Predict Reactivity

Bovine, Dog, Pig(>80% identity)
PROPERTIES

Form

Liquid

Buffer

Tris saline pH7.3, 0.02% sodium azide, 0.5% BSA.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide with sequence PENPATDKLQVLQ-C, from the N Terminus of the protein sequence according to NP_795352.2.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Patj, Crumbs Cell Polarity Complex Component,Cipp,Inadl,Inad-Like,Hinadl,Patj

Cellular Localization

Localized in the paranodal region of myelinating Schwann cells . Membrane-associated. Localizes to tight junctions in epithelial cells. Also found at the apical plasma membrane.

Background

This gene encodes a protein with multiple PDZ domains. PDZ domains mediate protein-protein interactions, and proteins with multiple PDZ domains often organize multimeric complexes at the plasma membrane. This protein localizes to tight junctions and to the apical membrane of epithelial cells. A similar protein in Drosophila is a scaffolding protein which tethers several members of a multimeric signaling complex in photoreceptors. [provided by RefSeq, Jul 2008]

Database

DATA IMAGES
GTX28225_414_IHC-P_18121410_200.jpg

GTX28225 IHC-P Image

IHC-P analysis of human testis using GTX28225 PATJ antibody, N-term.
Antigen retrieval : citrate buffer pH 6
Dilution : 3.8µg/ml

Package List Price ($)
$ 319