APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1-2 μg/ml |
| Assay dependent |
|
Note :
ELISA
For ELISA coating, recommend using BSA-free format (please contact us for PBS only format).
|
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
10mM PBS, 0.05% BSA
Preservative
0.05% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
Concentration
200 μg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant full-length human PAX5 protein
Purification
Protein A/G purified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
paired box 5 , ALL3 , BSAP
Cellular Localization
Nucleus
Background
This gene encodes a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. Paired box transcription factors are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. This gene encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis. This gene is located at 9p13, which is involved in t(9;14)(p13;q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas. This translocation brings the potent E-mu enhancer of the IgH gene into close proximity of the PAX5 promoter, suggesting that the deregulation of transcription of this gene contributes to the pathogenesis of these lymphomas. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]
Database
Research Area
DATA IMAGES
![Anti-PAX5 antibody [rPAX5/2060] used in Western Blot (WB). GTX02690](/templates/default/js/lightbox/images/loading.gif "Anti-PAX5 antibody [rPAX5/2060] used in Western Blot (WB). GTX02690")
|
GTX02690 WB Image
WB analysis of Raji whole cell lysate using GTX02690 PAX5 antibody [rPAX5/2060].
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REFERENCE
There are currently no references for PAX5 antibody [rPAX5/2060] (GTX02690). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for PAX5 antibody [rPAX5/2060] (GTX02690). Be the first to share your experience with this product.
![Anti-PAX5 antibody [rPAX5/2060] used in Western Blot (WB). GTX02690](/upload/website/prouct_img/small/GTX02690/GTX02690_20210319_WB_w_23053122_477.webp "Anti-PAX5 antibody [rPAX5/2060] used in Western Blot (WB). GTX02690")
![Anti-PAX5 antibody [rPAX5/2060] used in Western Blot (WB). GTX02690](/upload/website/prouct_img/normal/GTX02690/GTX02690_20210319_WB_w_23053122_477.webp "Anti-PAX5 antibody [rPAX5/2060] used in Western Blot (WB). GTX02690")