GeneTex
  • Country / Location Selection

United States (US)

PAX5 antibody [rPAX5/2060]

Anti-PAX5 antibody [rPAX5/2060] used in Western Blot (WB). GTX02690

Cat No. GTX02690

Host

Mouse

Clonality

Monoclonal

Clone Name

rPAX5/2060

Isotype

IgG1

Application

WB, ELISA

Reactivity

Human
Package
100 μg ($429)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1-2 μg/ml
ELISA Assay dependent

Note :

ELISA
For ELISA coating, recommend using BSA-free format (please contact us for PBS only format).

Not tested in other applications.

Calculated MW

42 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA, 0.05% azide (Please contact us for PBS only format)

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

200 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant full-length human PAX5 protein

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

paired box 5 , ALL3 , BSAP

Cellular Localization

Nucleus

Background

This gene encodes a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. Paired box transcription factors are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. This gene encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis. This gene is located at 9p13, which is involved in t(9;14)(p13;q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas. This translocation brings the potent E-mu enhancer of the IgH gene into close proximity of the PAX5 promoter, suggesting that the deregulation of transcription of this gene contributes to the pathogenesis of these lymphomas. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]

Database

Research Area

DATA IMAGES

Anti-PAX5 antibody [rPAX5/2060] used in Western Blot (WB). GTX02690

GTX02690 WB Image

WB analysis of Raji whole cell lysate using GTX02690 PAX5 antibody [rPAX5/2060].

REFERENCE

There are currently no references for PAX5 antibody [rPAX5/2060] (GTX02690). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for PAX5 antibody [rPAX5/2060] (GTX02690). Be the first to share your experience with this product.