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PCBP1 antibody, Internal

Anti-PCBP1 antibody, Internal used in Western Blot (WB). GTX47349
Anti-PCBP1 antibody, Internal used in IHC (Paraffin sections) (IHC-P). GTX47349
Anti-PCBP1 antibody, Internal used in Western Blot (WB). GTX47349
Anti-PCBP1 antibody, Internal used in IHC (Paraffin sections) (IHC-P). GTX47349

Cat No. GTX47349

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human
Package
50 μg ($359)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.2-2.5 ug/ml
IHC-P 2-10 ug/ml
Not tested in other applications.

Calculated MW

37 kDa. ( Note )

Positive Control

HCT116 , MCF-7

PROPERTIES

Form

Liquid

Buffer

1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide corresponding to an Internal region of Human PCBP1

Purification

Affinity Purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

poly(rC) binding protein 1 , HEL-S-85 , HNRPE1 , HNRPX , hnRNP-E1 , hnRNP-X

Cellular Localization

Nucleus,Cytoplasm

Background

This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 have paralogues (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly(rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. [provided by RefSeq, Jul 2008]

Database

DATA IMAGES

Anti-PCBP1 antibody, Internal used in Western Blot (WB). GTX47349

GTX47349 WB Image

WB analysis of MCF-7 cells using GTX47349 PCBP1 antibody at 1.0μg/ml.

Anti-PCBP1 antibody, Internal used in IHC (Paraffin sections) (IHC-P). GTX47349

GTX47349 IHC-P Image

IHC-P analysis of human breast tissue using GTX47349 PCBP1 antibody at 5μg/ml.

Anti-PCBP1 antibody, Internal used in Western Blot (WB). GTX47349

GTX47349 WB Image

WB analysis of HCT116 cells using GTX47349 PCBP1 antibody at 1μg/ml.

Anti-PCBP1 antibody, Internal used in IHC (Paraffin sections) (IHC-P). GTX47349

GTX47349 IHC-P Image

IHC-P analysis of human spleen tissue using GTX47349 PCBP1 antibody at 5μg/ml.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 359