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PCM1 antibody

Anti-PCM1 antibody used in IHC (Paraffin sections) (IHC-P). GTX33391
Anti-PCM1 antibody used in IHC (Paraffin sections) (IHC-P). GTX33391
Anti-PCM1 antibody used in Western Blot (WB). GTX33391

Cat No. GTX33391

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human, Mouse
Package
100 μl ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

229 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human PCM1 (NP_006188.3).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

pericentriolar material 1 , PTC4 , RET/PCM-1

Cellular Localization

Cytoplasm, cytoskeleton

Background

The protein encoded by this gene is a component of centriolar satellites, which are electron dense granules scattered around centrosomes. Inhibition studies show that this protein is essential for the correct localization of several centrosomal proteins, and for anchoring microtubules to the centrosome. Chromosomal aberrations involving this gene are associated with papillary thyroid carcinomas and a variety of hematological malignancies, including atypical chronic myeloid leukemia and T-cell lymphoma. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]

Database

Research Area

DATA IMAGES

Anti-PCM1 antibody used in IHC (Paraffin sections) (IHC-P). GTX33391

GTX33391 IHC-P Image

IHC-P analysis of human liver cancer tissue using GTX33391 PCM1 antibody.
Dilution : 1:100

Anti-PCM1 antibody used in IHC (Paraffin sections) (IHC-P). GTX33391

GTX33391 IHC-P Image

IHC-P analysis of mouse liver tissue using GTX33391 PCM1 antibody.
Dilution : 1:100

Anti-PCM1 antibody used in Western Blot (WB). GTX33391

GTX33391 WB Image

WB analysis of various samples using GTX33391 PCM1 antibody.
Dilution : 1:1000
Loading : 25μg per lane

REFERENCE

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REVIEW

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Package List Price ($)
$ 329