GeneTex
United States (US)

PD1 antibody [9X21]

Cat No. GTX52962

Host Mouse
Clonality Monoclonal
Clone Name 9X21
Isotype IgG2
Application WB, Neut
Reactivity Human
APPLICATION

Application Note

WB(1:500-1000)|Neutralization of PD-1 bioactivity

Calculated MW

32 kDa. ( Note )

Specificity/Sensitivity

This antibody was selected for its ability to specifically detect human PD-1 / CD279
PROPERTIES

Form

Liquid

Buffer

PBS

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Human recombinant PD-1

Purification

The IgG fraction of culture supernatant was purified by Protein G affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

CD279 Antibody , programmed cell death 1 Antibody , PD1 Antibody , PDCD1 Antibody , hPD-1 Antibody , hPD-l Antibody , SLEB2 Antibody

Background

This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul 2008]

Database

Research Area

SDS
PBS.pdf