WB(1:500-1000)|Neutralization of PD-1 bioactivity
This antibody was selected for its ability to specifically detect human PD-1 / CD279
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Human recombinant PD-1
The IgG fraction of culture supernatant was purified by Protein G affinity chromatography
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
CD279 Antibody , programmed cell death 1 Antibody , PD1 Antibody , PDCD1 Antibody , hPD-1 Antibody , hPD-l Antibody , SLEB2 Antibody
This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul 2008]