GeneTex
United States (US)

PD1 antibody

GTX31756_2917_WB_20180221_18121410_343.jpg
GTX31756_1399_IHC-P_20180221_18121410_892.jpg
GTX31756_1398_IHC-P_20180221_18121410_226.jpg
GTX31756_1400_IHC-P_20180221_18121410_718.jpg

Cat No. GTX31756

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, ELISA
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 μg/mL
IHC-P 2.5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

32 kDa. ( Note )

Positive Control

Human Brain Tissue Slide(GTX22203) , THP-1 Cell Lysate(GTX27913)
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

PD-1 antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human PD-1.The immunogen is located within amino acids 210 - 260 of PD-1.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Programmed Cell Death 1,Cd279,Pd-1,Pd1,Sleb2,Hpd-1,Hpd-L,Hsle1,Pdcd1

Background

This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX31756_2917_WB_20180221_18121410_343.jpg

GTX31756 WB Image

WB analysis of THP-1 cell lysate in the (A) absence and (B) presence of blocking peptide using GTX31756 PD1 antibody.
Working concentration : 1 μg/ml

GTX31756_1399_IHC-P_20180221_18121410_892.jpg

GTX31756 IHC-P Image

IHC-P analysis of human brain tissue using GTX31756 PD1 antibody.
Working concentration : 20 μg/ml

GTX31756_1398_IHC-P_20180221_18121410_226.jpg

GTX31756 IHC-P Image

IHC-P analysis of human brain tissue using GTX31756 PD1 antibody.
Working concentration : 2.5 μg/ml

GTX31756_1400_IHC-P_20180221_18121410_718.jpg

GTX31756 IHC-P Image

IHC-P analysis of human tonsil tissue using GTX31756 PD1 antibody.
Working concentration : 5 μg/ml