GeneTex
United States (US)

PDCD10 antibody

KO/KD
GTX35229_20180822_WB_1_18121410_116.jpg
GTX35229_20180822_WB_18121410_614.jpg

Cat No. GTX35229

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:200 - 1:2000
Not tested in other applications.

Calculated MW

25 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 50% glycerol, 0.02% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-212 of human PDCD10 (NP_009148.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

CCM3 Antibody , programmed cell death 10 Antibody , TFAR15 Antibody

Background

This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
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DATA IMAGES
GTX35229_20180822_WB_1_18121410_116.jpg

GTX35229 WB Image

KO/KD

WB analysis of wild type and PDCD10 knockout cell lysate using GTX35229 PDCD10 antibody.
Dilution : 1:1000
Loading : 25μg per lane

GTX35229_20180822_WB_18121410_614.jpg

GTX35229 WB Image

KO/KD

WB analysis of various samples using GTX35229 PDCD10 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Package List Price ($)
$ 329