GeneTex
United States (US)

PDCD2 antibody [N1C1]

GTX102409_40681_WB_19011506_741.jpg

Cat No. GTX102409

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:3000
Not tested in other applications.

Calculated MW

39 kDa. ( Note )

Positive Control

H1299 , HCT116

Predict Reactivity

Mouse, Rat, Bovine, Pig(>80% identity)
PROPERTIES

Form

Liquid

Buffer

1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1mg/ml

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human PDCD2. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

MGC12347 antibody, RP8 antibody, ZMYND7 antibody, PDCD2 antibody, programmed cell death protein 2 antibody, zinc finger protein Rp-8 antibody, zinc finger MYND domain-containing protein 7 antibody, programmed cell death 2 antibody

Cellular Localization

Nucleus

Background

This gene encodes a nuclear protein expressed in a variety of tissues. The rat homolog, Rp8, is transiently expressed in immature thymocytes and is thought to be involved in programmed cell death. Expression of the human gene has been shown to be repressed by BCL6, a transcriptional repressor required for lymph node germinal center development, suggesting that BCL6 regulates apoptosis by its effects on PDCD2. This gene is closely linked on chromosome 6 to the gene for TBP, the TATA binding protein. Two transcripts encoding different proteins have been identified. [provided by RefSeq]
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Database

Research Area

DATA IMAGES
GTX102409_40681_WB_19011506_741.jpg

GTX102409 WB Image

Sample (30 ug of whole cell lysate)
A: H1299
B: HCT116
10% SDS PAGE
GTX102409 diluted at 1:1000

SDS
PBS.pdf
Glycerol.pdf
Thimerosal.pdf