GeneTex

  • Country / Location Selection

United States (US)

PDE10A antibody

Anti-PDE10A antibody used in Western Blot (WB). GTX14622
Anti-PDE10A antibody used in Immunohistochemistry (IHC). GTX14622
Anti-PDE10A antibody used in Western Blot (WB). GTX14622
Anti-PDE10A antibody used in IHC (Paraffin sections) (IHC-P). GTX14622

Cat. No. GTX14622

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P, IP, ELISA, IHC

Reactivity

 Human, Mouse, Rat, Monkey
Package
100 μg ($489)
See all PDE10A products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:200
ICC/IF 1:10000
IHC-P Assay dependent
IP 1:100-1:150
ELISA 1:10000
IHC 1:100-1:150
Not tested in other applications.

Calculated MW

88 kDa. ( Note )

Product Note

This antibody has no cross-reactivity against any other PDE family members tested so far. This antibody will detect all PDE10A variants and subtypes.

PROPERTIES

Form

Liquid

Buffer

Tris/Glycine, 0.5% BSA, 30% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.7 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide (Human) taken against a common sequence near the 250-325 amino acids downstream of N-terminal region of PDE10A. Synthetic MAP.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

phosphodiesterase 10A , ADSD2 , HSPDE10A , IOLOD , LINC00473 , PDE10A19

Cellular Localization

Cytoplasm

Background

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This protein can hydrolyze both cAMP and cGMP to the corresponding nucleoside 5' monophosphate, but has higher affinity for cAMP, and is more efficient with cAMP as substrate. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Dec 2011]

Database

Research Area

DATA IMAGES

Anti-PDE10A antibody used in Western Blot (WB). GTX14622

GTX14622 WB Image

WB analysis of rat Frontal cortex, Parietalcortex, Striatum, Amygdala, Hypothalamus, Hippocampus, Olfactory bulb, Brain stem, Cerebellum,Spinal cord and whole brain lysates using GTX14622 PDE10A antibody.
Dilution : 1:500

Anti-PDE10A antibody used in Immunohistochemistry (IHC). GTX14622

GTX14622 IHC Image

IHC analysis of rat testis tissue using GTX14622 PDE10A antibody.
Figure A : Negative control
Figure B : Primary antibody
Dilution : 1:200

Anti-PDE10A antibody used in Western Blot (WB). GTX14622

GTX14622 WB Image

WB analysis of rat striatum tissue lysates using GTX14622 PDE10A antibody.
Dilution : 1:500

Anti-PDE10A antibody used in IHC (Paraffin sections) (IHC-P). GTX14622

GTX14622 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX14622 PDE10A antibody.
Dilution : 1:100

REFERENCE

There are currently no references for PDE10A antibody (GTX14622). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for PDE10A antibody (GTX14622). Be the first to share your experience with this product.
Submit a Review
Package List Price ($)
$ 489