*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
The peptide used to generate this antibody is available for purchase (GTX88149-PEP).
This antibody is expected to recognize isoform 1 (NP_005010.2) only.
Mouse, Rat, Bovine(>80% identity)
Tris saline pH7.3, 0.02% sodium azide, 0.5% BSA.
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
0.50 mg/ml (Please refer to the vial label for the specific concentration.)
Peptide with sequence C-DLHKNSEDLVNAE, from the C Terminus of the protein sequence according to NP_005010.2.
Purified by ammonium sulphate precipitation followed by antigen affinity chromatography
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Phosphodiesterase 1A,Cam-Pde 1A,Cam-Pde-1A,Hcam-1,Hcam1,Hspde1A,Pde1A
Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1; MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 [PubMed 11342109]; Fidock et al., 2002 [PubMed 11747989]).[supplied by OMIM, Oct 2009]
GTX88149 IHC-P Image
IHC-P analysis of human kidney using GTX88149 PDE1A antibody, C-term.
Antigen retrieval : citrate buffer pH 6
Dilution : 3.75µg/ml
GTX88149 WB Image
WB analysis of human cerebellum lysate using GTX88149 PDE1A antibody, C-term.
Dilution : 1µg/ml
Loading : 35µg protein in RIPA buffer