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PDE4A antibody, C-term

Cat. No. GTX80311

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IP, IHC

Reactivity

 Human, Mouse, Rat
Package
50 μl ($539)
See all PDE4A products

APPLICATION

Application Note

Recommended Starting Dilutions:
For WB: Use at 1:2000
Optimal dilutions should be determined experimentally by the researcher.

Calculated MW

98 kDa. ( Note )

Product Note

The antibody selectively detects proteins corresponding to members of the PDE4A sub-family, in human, mouse & rat

PROPERTIES

Form

Liquid

Buffer

Diluted serum

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Immunogen

Designed from the C-terminal region common to all 4A isoforms

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

phosphodiesterase 4A , DPDE2 , PDE4 , PDE46

Cellular Localization

Membrane

Background

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]

Database

Research Area

REFERENCE

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REVIEW

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Package List Price ($)
$ 539