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PDE4C antibody

Anti-PDE4C antibody used in IHC (Paraffin sections) (IHC-P). GTX14608

Cat. No. GTX14608

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P, IHC-Fr, IP, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($409)
See all PDE4C products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:2500
ICC/IF 1:200
IHC-P 1:200
IHC-Fr 1:200
IP 1:200
ELISA 1:10000
Not tested in other applications.

Calculated MW

80 kDa. ( Note )

Product Note

This antibody detects 3 isoforms of PDE4C subclasses: PDE4C1, PDE4C2, and PDE4C3.

PROPERTIES

Form

Liquid

Buffer

Tris/Glycine, 0.5% BSA, 30% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.65 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic cyclic carboxy-terminal peptide common to all PDE4C variants.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

phosphodiesterase 4C , DPDE1 , PDE21

Background

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]

Database

Research Area

DATA IMAGES

Anti-PDE4C antibody used in IHC (Paraffin sections) (IHC-P). GTX14608

GTX14608 IHC-P Image

IHC-P analysis of human ovarian medulla tissue using GTX14608 PDE4C antibody.
Dilution : 1:3000

REFERENCE

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REVIEW

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Package List Price ($)
$ 409