Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1:500 |
1:200 |
1:150 |
1:10000 |
1:200 |
Not tested in other applications.
Calculated MW
Product Note
This antibody does not cross-react with other members of the PDE4D family or with other PDE4 proteins (PDE4A, PDE4B and PDE4C) or with other PDE family members.
Form
Liquid
Buffer
Tris/Glycine, 0.5% BSA, 30% Glycerol
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.65 mg/ml (Please refer to the vial label for the specific concentration.)
Immunogen
A 20 amino acid synthetic peptide taken from the N-terminus corresopnding to the PDE4D5 variant.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
RRID
AB_368861
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
Synonyms
phosphodiesterase 4D , ACRDYS2 , DPDE3 , HSPDE4D , PDE43 , PDE4DN2 , STRK1
Cellular Localization
Apical cell membrane , Cytoplasm , Membrane , Cytoplasm, cytoskeleton
Background
This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.[provided by RefSeq, Sep 2009]
Database
Research Area