Preservative: 0.02% Sodium Azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
0.5 mg/ml (Please refer to the vial label for the specific concentration.)
Synthetic peptide (unfortunately, the amino acid sequence is considered to be commercially sensitive) (C terminal).
Immunogen affinity purified
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Cyclic GMP-phosphodiesterase plays a key role in the normal functioning of retinal rod photoreceptor cells. The enzyme is composed of alpha- and beta-catalytic subunits which are inhibited by 2 identical gamma subunits. The PDE6 gamma subunit has been cloned and sequenced from human retina. The 1,012-bp cDNA had a coding region of 261 bp that was highly homologous to those of the corresponding cDNA from bovine and mouse retinas. Comparison of the deduced amino acid sequences from 3 species indicated evolutionary conservation.