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PDE7B antibody

Anti-PDE7B antibody used in Immunohistochemistry (IHC). GTX14617
Anti-PDE7B antibody used in Western Blot (WB). GTX14617

Cat. No. GTX14617

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IP, ELISA, IHC

Reactivity

 Human
Package
100 μg ($409)
See all PDE7B products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:1000
ICC/IF 1:200
IP 1:250
ELISA 1:10000
IHC 1:200
Not tested in other applications.

Calculated MW

52 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Tris/Glycine, 0.5% BSA, 30% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Immunogen

Synthetic cyclic peptide common to all PDE7B variants.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_372718

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

phosphodiesterase 7B , bA472E5.1

Background

The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a cAMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family.[provided by RefSeq, Apr 2009]

Database

Research Area

DATA IMAGES

Anti-PDE7B antibody used in Immunohistochemistry (IHC). GTX14617

GTX14617 IHC Image

IHC analysis of human ovarian medulla tissue using GTX14617 PDE7B antibody.
Dilution : 1:150

Anti-PDE7B antibody used in Western Blot (WB). GTX14617

GTX14617 WB Image

WB analysis of PDE7B recombinant protein using GTX14617 PDE7B antibody.
Dilution : 1:1000

REFERENCE

Application Reference

Guibinga GH et al. PLoS One 2013; 8 (5) : e63333 HPRT-deficiency dysregulates cAMP-PKA signaling and phosphodiesterase 10A expression: mechanistic insight and potential target for Lesch-Nyhan Disease?
Application : WB
Reactivity : Human
Submit a Reference

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Package List Price ($)
$ 409