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PDE8A antibody

Cat No. GTX14620

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, ICC/IF, IP, ELISA, IHC

Reactivity

Human, Mouse, Rat, Bovine, Monkey
Package
100 μg ($339)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500
ICC/IF 1:250
IP 1:250
ELISA 1:10000
IHC 1:250
Not tested in other applications.

Calculated MW

93 kDa. ( Note )

Product Note

This antibody will label only PDE8A variants. This antibody will not cross react with other PDE family members.

PROPERTIES

Form

Liquid

Buffer

Tris/Glycine pH7.4-7.9, 30% Glycerol, 0.5% BSA

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.75 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic cyclic peptide from C terminus common to all PDE8A variants.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

phosphodiesterase 8A , HsT19550

Background

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE8 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011]

Database

Research Area

REFERENCE

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REVIEW

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Package List Price ($)
$ 339