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PDE8B antibody

Anti-PDE8B antibody used in Western Blot (WB). GTX14621
Anti-PDE8B antibody used in Immunohistochemistry (IHC). GTX14621

Cat. No. GTX14621

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IP, ELISA, IHC

Reactivity

 Human, Mouse, Rat, Bovine, Monkey
Package
100 μg ($419)
See all PDE8B products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:2000
ICC/IF 1:200
IP 1:250
ELISA 1:10000
IHC 1:200
Not tested in other applications.

Calculated MW

99 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Tris/Glycine, 0.5% BSA, 30% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic cyclic peptide common to all PDE8B variants.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

phosphodiesterase 8B , ADSD , PPNAD3

Background

The protein encoded by this gene is a cyclic nucleotide phosphodiesterase (PDE) that catalyzes the hydrolysis of the second messenger cAMP. The encoded protein, which does not hydrolyze cGMP, is resistant to several PDE inhibitors. Defects in this gene are a cause of autosomal dominant striatal degeneration (ADSD). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2010]

Database

Research Area

DATA IMAGES

Anti-PDE8B antibody used in Western Blot (WB). GTX14621

GTX14621 WB Image

WB analysis of rat testis and heart tissue lysates using GTX14621 PDE8B antibody.
Dilution : 1:300

Anti-PDE8B antibody used in Immunohistochemistry (IHC). GTX14621

GTX14621 IHC Image

IHC analysis of human ovarian medulla tissue using GTX14621 PDE8B antibody.
Dilution : 1:2000

REFERENCE

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REVIEW

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Package List Price ($)
$ 419