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PDE8B antibody

Anti-PDE8B antibody used in IHC (Paraffin sections) (IHC-P). GTX85801

Cat. No. GTX85801

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human, Monkey
Package
50 μg ($459)
See all PDE8B products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 5 μg/ml

Note :

IHC-P
Heat induced antigen retrieval in pH 6.0 citrate buffer
Not tested in other applications.

Calculated MW

99 kDa. ( Note )

Predict Reactivity

Mouse, Rat, Dog, Pig, Bat, Elephant, Gibbon, Gorilla, Horse, Marmoset, Opossum, Platypus(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.3 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic 16 amino acid peptide from internal region of human PDE8B.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

phosphodiesterase 8B , ADSD , PDE8B , PPNAD3

Background

The protein encoded by this gene is a cyclic nucleotide phosphodiesterase (PDE) that catalyzes the hydrolysis of the second messenger cAMP. The encoded protein, which does not hydrolyze cGMP, is resistant to several PDE inhibitors. Defects in this gene are a cause of autosomal dominant striatal degeneration (ADSD). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2010]

Database

Research Area

DATA IMAGES

Anti-PDE8B antibody used in IHC (Paraffin sections) (IHC-P). GTX85801

GTX85801 IHC-P Image

IHC-P analysis of human thyroid tissue using GTX85801 PDE8B antibody.
Antigen retrieval : Heat-induced antigen retrieval

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 459