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United States (US)

PDGF-BB antibody

Anti-PDGF-BB antibody used in IHC (Paraffin sections) (IHC-P). GTX31199
Anti-PDGF-BB antibody used in IHC (Paraffin sections) (IHC-P). GTX31199

Cat No. GTX31199

Host Rabbit
Clonality Polyclonal
Application WB, IHC-P, ELISA, Neut
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
IHC-P Assay dependent
ELISA Assay dependent
Neut Assay dependent
Not tested in other applications.

Calculated MW

27 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS, pH 7.2

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

E.coli derived Recombinant Human PDGF-BB

Purification

Affinity Purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Platelet Derived Growth Factor Subunit B,Ibgc5,Pdgf-2,Pdgf2,Sis,Ssv,C-Sis,Pdgfb

Background

The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 17, at sites where this gene and that for collagen type 1, alpha 1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2013]

Database

Research Area

DATA IMAGES
Anti-PDGF-BB antibody used in IHC (Paraffin sections) (IHC-P). GTX31199

GTX31199 IHC-P Image

IHC-P analysis of normal human skin using PDGF-BB antibody at a concentration of 1.0 μg/ml. An HRP-labeled polymer detection system was used with a non-alcohol soluble AEC chromogen and a proteinase K antigen retrieval.

Anti-PDGF-BB antibody used in IHC (Paraffin sections) (IHC-P). GTX31199

GTX31199 IHC-P Image

IHC-P analysis of normal human skin using PDGF-BB antibody at a concentration of 1.0 μg/ml. An HRP-labeled polymer detection system was used with a non-alcohol soluble AEC chromogen and a proteinase K antigen retrieval.