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PDGF Receptor alpha antibody [3G28]

Anti-PDGF Receptor alpha antibody [3G28] used in IHC (Paraffin sections) (IHC-P). GTX53096

Cat. No. GTX53096

Host

 Rat

Clonality

 Monoclonal

Clone Name

 3G28

Isotype

 IgG2

Application

 WB, IHC-P

Reactivity

 Mouse
Package
100 μg ($399)
See all PDGF Receptor alpha products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:400 - 1:800
IHC-P 1:50 - 1:100
Not tested in other applications.

Calculated MW

123 kDa. ( Note )

Product Note

This antibody recognizes mouse PDGF Receptor alpha in western blot. No cross-reactivity to mouse PDGF Receptor beta.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

200 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Mouse

Immunogen

Mouse PDGFR α extra-cellular domain

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Cellular Localization

Cell membrane

Background

This gene encodes a member of the receptor tyrosine kinase family of proteins. Binding of platelet-derived growth factor protein ligands to this receptor triggers receptor dimerization and autophosphorylation, resulting in the activation of several downstream signaling pathways. Signaling through the encoded receptor plays a role in gastrulation and the development of nearly all organ systems. Mice lacking a functional copy of this gene reportedly exhibit defects in lung, skeleton, testis and the central nervous system, and die soon after birth. Alternative splicing and intronic polyadenylation of gene transcripts have been implicated in muscle regeneration and fibrosis in adult mice. [provided by RefSeq, Jan 2017]

Database

Research Area

DATA IMAGES

Anti-PDGF Receptor alpha antibody [3G28] used in IHC (Paraffin sections) (IHC-P). GTX53096

GTX53096 IHC-P Image

IHC-P analysis of pancreas tissue sections from LPS exposed mouse using GTX53096 PDGF Receptor alpha antibody [3G28].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 399