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PDGF Receptor alpha antibody (Ready-to-use)

Anti-PDGF Receptor alpha antibody (Ready-to-use) used in IHC (Paraffin sections) (IHC-P). GTX15501
Anti-PDGF Receptor alpha antibody (Ready-to-use) used in IHC (Paraffin sections) (IHC-P). GTX15501

Cat No. GTX15501

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

IHC-P

Reactivity

Human, Mouse
Package
7 ml ($319)

APPLICATION

Application Note

IHC-P: Use at an assay dependent dilution. Staining of formalin fixed tissues requires boiling tissue sections in 10mMcitrate buffer, pH 6.0 for 10 min followed by cooling at room temperature for 20 min. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

123 kDa. ( Note )

Positive Control

Human skin and Ovarian Carcinoma

PROPERTIES

Form

Liquid

Buffer

PBS, pH 7.4 containing 1%BSA and 0.1% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Antigen Species

Human

Immunogen

Synthetic peptide (unfortunately, the amino acid sequence is considered to be commercially sensitive) corresponding to C terminal of human PDGFR alpha.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

platelet derived growth factor receptor alpha , CD140A , PDGFR-2 , PDGFR2

Cellular Localization

Cell membrane , Golgi apparatus

Background

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. [provided by RefSeq, Mar 2012]

Database

Research Area

DATA IMAGES

Anti-PDGF Receptor alpha antibody (Ready-to-use) used in IHC (Paraffin sections) (IHC-P). GTX15501

GTX15501 IHC-P Image

GTX15501 staining PDGF Receptor alpha in human ovarian carcinoma by Immunohistochemistry (FFPE-sections).

Anti-PDGF Receptor alpha antibody (Ready-to-use) used in IHC (Paraffin sections) (IHC-P). GTX15501

GTX15501 IHC-P Image

Human Ovarian Carcinoma stained with anti-PDGFR alpha antibody (GTX15501)

REFERENCE

There are currently no references for PDGF Receptor alpha antibody (Ready-to-use) (GTX15501). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for PDGF Receptor alpha antibody (Ready-to-use) (GTX15501). Be the first to share your experience with this product.
SDS
PBS.pdf
Sodium Azide.pdf