APPLICATION
Application Note
IHC-P: Use at an assay dependent dilution. Staining of formalin fixed tissues requires boiling tissue sections in 10mMcitrate buffer, pH 6.0 for 10 min followed by cooling at room temperature for 20 min. Optimal dilutions/concentrations should be determined by the end user.
Calculated MW
Positive Control
Human skin and Ovarian Carcinoma
PROPERTIES
Form
Liquid
Buffer
PBS, 1% BSA
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Antigen Species
Human
Immunogen
Synthetic peptide (unfortunately, the amino acid sequence is considered to be commercially sensitive) corresponding to C terminal of human PDGFR alpha.
Purification
Unpurified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
platelet derived growth factor receptor alpha , CD140A , PDGFR-2 , PDGFR2
Cellular Localization
Cell membrane , Golgi apparatus
Background
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. [provided by RefSeq, Mar 2012]
Database
Research Area
DATA IMAGES
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GTX15501 IHC-P Image
Human Ovarian Carcinoma stained with anti-PDGFR alpha antibody (GTX15501)
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GTX15501 IHC-P Image
GTX15501 staining PDGF Receptor alpha in human ovarian carcinoma by Immunohistochemistry (FFPE-sections).
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REFERENCE
There are currently no references for PDGF Receptor alpha antibody (Ready-to-use) (GTX15501). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for PDGF Receptor alpha antibody (Ready-to-use) (GTX15501). Be the first to share your experience with this product.