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PDGF Receptor alpha antibody

Anti-PDGF Receptor alpha antibody used in IHC (Paraffin sections) (IHC-P). GTX66642
Anti-PDGF Receptor alpha antibody used in Western Blot (WB). GTX66642
Anti-PDGF Receptor alpha antibody used in Western Blot (WB). GTX66642

Cat No. GTX66642

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human, Mouse, Rat
Package
100 μl ($349)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:1000
IHC-P 1:50-1:200
Not tested in other applications.

Calculated MW

123 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS pH7.2, 0.05% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide, corresponding to amino acids 1020-1070 of Human PDGFR-α.

Purification

Purified by antigen-affinity chromatography
From serum

Purity

> 95% (by SDS-PAGE)

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

platelet derived growth factor receptor alpha , CD140A , PDGFR-2 , PDGFR2

Cellular Localization

Cell membrane,Golgi apparatus

Background

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. [provided by RefSeq, Mar 2012]

Database

Research Area

DATA IMAGES

Anti-PDGF Receptor alpha antibody used in IHC (Paraffin sections) (IHC-P). GTX66642

GTX66642 IHC-P Image

IHC-P analysis of human breast carcinoma tissue using GTX66642 PDGF Receptor alpha antibody.
Dilution : 1:50

Anti-PDGF Receptor alpha antibody used in Western Blot (WB). GTX66642

GTX66642 WB Image

WB analysis of various samples using GTX66642 PDGF Receptor alpha antibody.
Lane1 : SGC-7901 whole cell lysate(40ug)
Lane2 : SK-OVCAR3 whole cell lysate(40ug)
Lane3 : HEK293T whole cell lysate(40ug)
Lane4 : The brain tissue lysate of Mouse(40ug)
Lane5 : The brain tissue lysate of Rat(40ug)
Dilution : 1:500

Anti-PDGF Receptor alpha antibody used in Western Blot (WB). GTX66642

GTX66642 WB Image

WB analysis of various samples using GTX66642 PDGF Receptor alpha antibody.
Lane1 : HEK293T whole cell lysate
Lane2 : sp2/0 whole cell lysate
Lane3 : PC12 whole cell lysate
Dilution : 1:500

REFERENCE

REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf