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PDGF Receptor beta antibody [1A2]

Anti-PDGF Receptor beta antibody [1A2] used in Western Blot (WB). GTX83371
Anti-PDGF Receptor beta antibody [1A2] used in IHC (Paraffin sections) (IHC-P). GTX83371

Cat. No. GTX83371

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 1A2

Isotype

 IgG1

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse
Package
100 μl ($399)
See all PDGF Receptor beta products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1/500 - 1/2000
IHC-P Assay dependent
ELISA 1/10000
Not tested in other applications.

Calculated MW

124 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Ascites

Preservative

0.03% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Purified recombinant fragment of human PDGFRβ expressed in E. Coli.

Purification

Unpurified

Conjugation

Unconjugated

RRID

AB_11165546

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

platelet derived growth factor receptor beta , CD140B , IBGC4 , IMF1 , JTK12 , KOGS , PDGFR , PDGFR-1 , PDGFR1 , PENTT

Cellular Localization

Cell membrane; Single-pass type I membrane protein,Cytoplasmic vesicle

Background

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-PDGF Receptor beta antibody [1A2] used in Western Blot (WB). GTX83371

GTX83371 WB Image

WB analysis of NIH3T3 cell lysate using GTX83371 PDGF Receptor beta antibody [1A2].

Anti-PDGF Receptor beta antibody [1A2] used in IHC (Paraffin sections) (IHC-P). GTX83371

GTX83371 IHC-P Image

The data was published in the journal Sci Rep in 2018.PMID: 29802255

REFERENCE

Application Reference

Ono Y et al. Sci Rep 2018; 8 (1) : 8171 CD11c+ M1-like macrophages (MΦs) but not CD206+ M2-like MΦ are involved in folliculogenesis in mice ovary.
Application : IHC-P
Reactivity : Mouse
Submit a Reference

REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399