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PDGF Receptor beta antibody [5C37]

Anti-PDGF Receptor beta antibody [5C37] used in IHC (Paraffin sections) (IHC-P). GTX52458

Cat No. GTX52458

Host

Mouse

Clonality

Monoclonal

Clone Name

5C37

Isotype

IgG1

Application

WB, IHC-P, FACS

Reactivity

Human
Package
100 μg ($459)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:400 - 1:1000
IHC-P 1:50 - 1:500
FACS 15μl / 10⁶ cells
Not tested in other applications.

Calculated MW

124 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

200 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant hPGFDR beta N-terminal

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

CD140B , IBGC4 , IMF1 , JTK12 , KOGS , PDGFR , PDGFR1 , PDGFRB , PENTT , platelet derived growth factor receptor beta , PDGF Receptor beta , CD140b , PDGFR beta

Cellular Localization

Cell membrane,Cytoplasmic vesicle,Lysosome lumen

Background

The protein encoded by this gene is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer (PDGFB or PDGFD) or a heterodimer (PDGFA and PDGFB). This gene is essential for normal development of the cardiovascular system and aids in rearrangement of the actin cytoskeleton. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the ETV6 gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq, Aug 2017]

Database

Research Area

DATA IMAGES

Anti-PDGF Receptor beta antibody [5C37] used in IHC (Paraffin sections) (IHC-P). GTX52458

GTX52458 IHC-P Image

IHC-P analysis of formalin fixed human placenta tissue using GTX52458 PDGF Receptor beta antibody [5C37].

REFERENCE

There are currently no references for PDGF Receptor beta antibody [5C37] (GTX52458). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for PDGF Receptor beta antibody [5C37] (GTX52458). Be the first to share your experience with this product.
SDS
PBS.pdf