APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:500 - 1:2000 |
| 1:50 - 1:200 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS, 50% Glycerol
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
A synthesized peptide derived from hmuan PDGF Receptor beta
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
platelet derived growth factor receptor beta , CD140B , IBGC4 , IMF1 , JTK12 , KOGS , PDGFR , PDGFR-1 , PDGFR1 , PENTT
Cellular Localization
Cell membrane; Single-pass type I membrane protein,Cytoplasmic vesicle
Background
The protein encoded by this gene is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer (PDGFB or PDGFD) or a heterodimer (PDGFA and PDGFB). This gene is essential for normal development of the cardiovascular system and aids in rearrangement of the actin cytoskeleton. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the ETV6 gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq, Aug 2017]
Database
Research Area
DATA IMAGES
![Anti-PDGF Receptor beta antibody [GT1140] used in Western Blot (WB). GTX00798](/templates/default/js/lightbox/images/loading.gif "Anti-PDGF Receptor beta antibody [GT1140] used in Western Blot (WB). GTX00798")
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GTX00798 WB Image
Various whole cell extracts (30 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with PDGF Receptor beta antibody [GT1140] (GTX00798) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
The observed M.W. is based on the publication: PMID: 31039042
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GTX00798 WB Image
WB analysis of various samples using GTX00798 PDGF Receptor beta antibody [GT1140].
Dilution : 1:1000
Loading : 25 μg
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GTX00798 ICC/IF Image
ICC/IF analysis of NIH-3T3 cells using GTX00798 PDGF Receptor beta antibody [GT1140].
Red: Primary antibody
Blue: DAPI
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REFERENCE
There are currently no references for PDGF Receptor beta antibody [GT1140] (GTX00798). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for PDGF Receptor beta antibody [GT1140] (GTX00798). Be the first to share your experience with this product.
![Anti-PDGF Receptor beta antibody [GT1140] used in Western Blot (WB). GTX00798](/upload/website/prouct_img/small/GTX00798/GTX00798_4000000009_20200410_WB_w_23053121_570.webp "Anti-PDGF Receptor beta antibody [GT1140] used in Western Blot (WB). GTX00798")
![Anti-PDGF Receptor beta antibody [GT1140] used in Western Blot (WB). GTX00798](/upload/website/prouct_img/small/GTX00798/GTX00798_20200508_WB_w_23053121_970.webp "Anti-PDGF Receptor beta antibody [GT1140] used in Western Blot (WB). GTX00798")
![Anti-PDGF Receptor beta antibody [GT1140] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX00798](/upload/website/prouct_img/small/GTX00798/GTX00798_20191101_AP_002_35_w_23053121_180.webp "Anti-PDGF Receptor beta antibody [GT1140] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX00798")
![Anti-PDGF Receptor beta antibody [GT1140] used in Western Blot (WB). GTX00798](/upload/website/prouct_img/normal/GTX00798/GTX00798_4000000009_20200410_WB_w_23053121_570.webp "Anti-PDGF Receptor beta antibody [GT1140] used in Western Blot (WB). GTX00798")
![Anti-PDGF Receptor beta antibody [GT1140] used in Western Blot (WB). GTX00798](/upload/website/prouct_img/normal/GTX00798/GTX00798_20200508_WB_w_23053121_970.webp "Anti-PDGF Receptor beta antibody [GT1140] used in Western Blot (WB). GTX00798")
![Anti-PDGF Receptor beta antibody [GT1140] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX00798](/upload/website/prouct_img/normal/GTX00798/GTX00798_20191101_AP_002_35_w_23053121_180.webp "Anti-PDGF Receptor beta antibody [GT1140] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX00798")