GeneTex

  • Country / Location Selection

United States (US)

PDGF Receptor beta antibody

Anti-PDGF Receptor beta antibody used in Western Blot (WB). GTX25511
Anti-PDGF Receptor beta antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX25511
Anti-PDGF Receptor beta antibody used in IHC (Paraffin sections) (IHC-P). GTX25511
Anti-PDGF Receptor beta antibody used in Flow cytometry (FACS). GTX25511

Cat. No. GTX25511

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P, FACS

Reactivity

 Human
Package
400 μl ($399)
See all PDGF Receptor beta products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000
ICC/IF 1:10-1:50
IHC-P 1:10-1:50
FACS 1:10-1:50
Not tested in other applications.

Calculated MW

124 kDa. ( Note )

Positive Control

THP-1 cell lysate

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide between 40-72 amino acids from the N-terminal region of human PDGFRB.

Purification

Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Conjugation

Unconjugated

RRID

AB_380571

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

platelet derived growth factor receptor beta , CD140B , IBGC4 , IMF1 , JTK12 , KOGS , PDGFR , PDGFR-1 , PDGFR1 , PENTT

Cellular Localization

Cell membrane; Single-pass type I membrane protein,Cytoplasmic vesicle

Background

The protein encoded by this gene is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer (PDGFB or PDGFD) or a heterodimer (PDGFA and PDGFB). This gene is essential for normal development of the cardiovascular system and aids in rearrangement of the actin cytoskeleton. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the ETV6 gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq, Aug 2017]

Database

Research Area

DATA IMAGES

Anti-PDGF Receptor beta antibody used in Western Blot (WB). GTX25511

GTX25511 WB Image

WB analysis of cell lysate (35ug/lane) using GTX25511 PDGF Receptor beta antibody.

Anti-PDGF Receptor beta antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX25511

GTX25511 ICC/IF Image

ICC/IF analysis of WiDr cells using GTX25511 PDGF Receptor beta antibody.
Green : PDGF Receptor beta
Blue : DAPI

Anti-PDGF Receptor beta antibody used in IHC (Paraffin sections) (IHC-P). GTX25511

GTX25511 IHC-P Image

IHC-P analysis of human breast carcinoma using GTX25511 PDGF Receptor beta antibody.

Anti-PDGF Receptor beta antibody used in Flow cytometry (FACS). GTX25511

GTX25511 FACS Image

FACS analysis of SK-Br-3 cells using GTX25511 PDGF Receptor beta antibody.
Top histogram : negative control
Bottom histogram : SK-Br-3 cells

REFERENCE

Application Reference

Doddapaneni R et al. Oncotarget 2019; 10 (4) : 480-493 Fibroblast growth factor receptor 1 (FGFR1) as a therapeutic target in adenoid cystic carcinoma of the lacrimal gland.
Application : ICC/IF
Reactivity : Human
Submit a Reference

REVIEW

There are currently no reviews for PDGF Receptor beta antibody (GTX25511). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399