APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:500 - 1:2000 |
| 1:50 - 1:200 |
| 1:50 - 1:200 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS, 50% Glycerol
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 887-1106 of human PDGFRB (NP_002600.1).
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
platelet derived growth factor receptor beta , CD140B , IBGC4 , IMF1 , JTK12 , KOGS , PDGFR , PDGFR-1 , PDGFR1 , PENTT
Cellular Localization
Cell membrane; Single-pass type I membrane protein,Cytoplasmic vesicle
Background
The protein encoded by this gene is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer (PDGFB or PDGFD) or a heterodimer (PDGFA and PDGFB). This gene is essential for normal development of the cardiovascular system and aids in rearrangement of the actin cytoskeleton. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the ETV6 gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq, Aug 2017]
Database
Research Area
DATA IMAGES
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GTX32777 ICC/IF Image
ICC/IF analysis of C6 cells using GTX32777 PDGF Receptor beta antibody.
Blue : DAPI
Dilution : 1:100
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GTX32777 IHC-P Image
IHC-P analysis of human placenta tissue using GTX32777 PDGF Receptor beta antibody.
Dilution : 1:100
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GTX32777 WB Image
WB analysis of various sample lysates using GTX32777 PDGF Receptor beta antibody.
Dilution : 1:1000
Loading : 25μg per lane
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GTX32777 ICC/IF Image
ICC/IF analysis of NIH/3T3 cells using GTX32777 PDGF Receptor beta antibody.
Blue : DAPI
Dilution : 1:100
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GTX32777 IHC-P Image
IHC-P analysis of rat kidney tissue using GTX32777 PDGF Receptor beta antibody.
Dilution : 1:100
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REFERENCE
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REVIEW
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