APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:1000 |
| Assay dependent |
Not tested in other applications.
Calculated MW
Product Note
This antibody shows approximately some degree (40%) cross-reactivity with PDGF-AB and no cross-reactivity with recombinant PDGF-AA.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
No preservative
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
200 μg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Human PDGF B recombinant protein
Purification
Protein G purified
From tissue culture supernatant
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
IBGC5 , PDGF2 , PDGFB , SIS , SSV , csis , platelet derived growth factor subunit B , PDGF-B
Cellular Localization
Secreted
Background
This gene encodes a member of the protein family comprised of both platelet-derived growth factors (PDGF) and vascular endothelial growth factors (VEGF). The encoded preproprotein is proteolytically processed to generate platelet-derived growth factor subunit B, which can homodimerize, or alternatively, heterodimerize with the related platelet-derived growth factor subunit A. These proteins bind and activate PDGF receptor tyrosine kinases, which play a role in a wide range of developmental processes. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 17, at sites where this gene and that for collagen type 1, alpha 1 are located, are associated with dermatofibrosarcoma protuberans, a rare skin tumor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
Database
Research Area
DATA IMAGES
![Anti-PDGF beta antibody [5F66] used in Western Blot (WB). GTX52467](/templates/default/js/lightbox/images/loading.gif "Anti-PDGF beta antibody [5F66] used in Western Blot (WB). GTX52467")
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GTX52467 WB Image
WB analysis of human placenta tissue lysates using GTX52467 PDGF beta antibody [5F66].
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GTX52467 IHC-P Image
IHC-P analysis of formalin fixed human placenta tissue using GTX52467 PDGF beta antibody [5F66].
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REFERENCE
There are currently no references for PDGF beta antibody [5F66] (GTX52467). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for PDGF beta antibody [5F66] (GTX52467). Be the first to share your experience with this product.
![Anti-PDGF beta antibody [5F66] used in Western Blot (WB). GTX52467](/upload/website/prouct_img/small/GTX52467/GTX52467_20220822_WB_22082302_220.webp "Anti-PDGF beta antibody [5F66] used in Western Blot (WB). GTX52467")
![Anti-PDGF beta antibody [5F66] used in IHC (Paraffin sections) (IHC-P). GTX52467](/upload/website/prouct_img/small/GTX52467/GTX52467_20191119_IHC-P_w_23060900_675.webp "Anti-PDGF beta antibody [5F66] used in IHC (Paraffin sections) (IHC-P). GTX52467")
![Anti-PDGF beta antibody [5F66] used in Western Blot (WB). GTX52467](/upload/website/prouct_img/normal/GTX52467/GTX52467_20220822_WB_22082302_220.webp "Anti-PDGF beta antibody [5F66] used in Western Blot (WB). GTX52467")
![Anti-PDGF beta antibody [5F66] used in IHC (Paraffin sections) (IHC-P). GTX52467](/upload/website/prouct_img/normal/GTX52467/GTX52467_20191119_IHC-P_w_23060900_675.webp "Anti-PDGF beta antibody [5F66] used in IHC (Paraffin sections) (IHC-P). GTX52467")