*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
A549 , HeLa , HepG2 , HCT116
Mouse, Bovine(>80% identity)
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
0.79mg/ml(Please refer to the vial label for the specific concentration.)
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human PDGF beta. The exact sequence is proprietary.
Purified by antigen-affinity chromatography.
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
FLJ12858 antibody, PDGF2 antibody, SIS antibody, SSV antibody, c-sis antibody, PDGFB antibody, "Platelet-derived growth factor, beta polypeptide (oncogene SIS) antibody", platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) antibody, becaplermin antibody, PDGF-2 antibody, platelet-derived growth factor 2 antibody, platelet-derived growth factor B chain antibody, proto-oncogene c-Sis antibody, PDGF subunit B antibody, "PDGF, B chain antibody", platelet-derived growth factor subunit B antibody, "platelet-derived growth factor, B chain antibody"
The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 7, at sites where this gene and that for COL1A1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq]
GTX100683 WB Image
Sample (30 ug of whole cell lysate)
12% SDS PAGE
GTX100683 diluted at 1:500
GTX100683 IHC-P Image
Immunohistochemical analysis of paraffin-embedded human breast cancer, using PDGFB(GTX100683) antibody at 1:250 dilution.
Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min