GeneTex
United States (US)

PDI antibody

GTX31623_1294_IHC-P_20180221_18121410_387.jpg
GTX31623_2808_WB_20180221_18121410_956.jpg
GTX31623_1295_IHC-P_20180221_18121410_863.jpg

Cat No. GTX31623

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, ELISA
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 - 2 μg/mL
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

57 kDa. ( Note )

Positive Control

Rat Small Intestine Tissue Lysate(GTX24038)
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

PDI antibody was raised against a 17 amino acid peptide near the center of human PDI.The immunogen is located within amino acids 190 - 240 of PDI.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Prolyl 4-Hydroxylase Subunit Beta,Clcrp1,Dsi,Erba2L,Git,P4Hbeta,Pdi,Pdia1,Phdb,Po4Db,Po4Hb,Prohb,P4Hb

Background

This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX31623_1294_IHC-P_20180221_18121410_387.jpg

GTX31623 IHC-P Image

IHC-P analysis of rat small intestine tissue using GTX31623 PDI antibody.
Working concentration : 5 μg/ml

GTX31623_2808_WB_20180221_18121410_956.jpg

GTX31623 WB Image

WB analysis of rat small intestine tissue lysate using GTX31623 PDI antibody.
Working concentration : (A) 1 and (B) 2 μg/ml

GTX31623_1295_IHC-P_20180221_18121410_863.jpg

GTX31623 IHC-P Image

IHC-P analysis of rat small intestine tissue using GTX31623 PDI antibody.
Working concentration : 20 μg/ml

Package List Price ($)
$ 329