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PDX1 antibody

Anti-PDX1 antibody used in IHC (Paraffin sections) (IHC-P). GTX37568

Cat. No. GTX37568

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 IHC-P

Reactivity

 Rat
Package
100 μg ($459)
See all PDX1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:400-800
Not tested in other applications.

Calculated MW

31 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM TBS, 0.5% BSA, 25% Glycerol

Preservative

0.015% ProClin 300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide derived between 198-274 amino acids of human PDX1

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

pancreatic and duodenal homeobox 1 , GSF , IDX-1 , IPF1 , IUF1 , MODY4 , PAGEN1 , PDX-1 , STF-1

Cellular Localization

Nucleus,Cytoplasm, cytosol

Background

The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (IDDM), as well as maturity onset diabetes of the young type 4 (MODY4). [provided by RefSeq, Aug 2017]

Database

Research Area

DATA IMAGES

Anti-PDX1 antibody used in IHC (Paraffin sections) (IHC-P). GTX37568

GTX37568 IHC-P Image

IHC-P analysis of rat pancreas tissue using GTX37568 PDX1 antibody.

REFERENCE

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REVIEW

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SDS
Glycerol.pdf
Proclin.pdf
Package List Price ($)
$ 459