GeneTex
United States (US)

PDX1 antibody

GTX37568_20190129_IHC-P_19012901_251.jpg

Cat No. GTX37568

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application IHC-P
Reactivity Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 1:400-800
Not tested in other applications.

Calculated MW

31 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

0.01M TBS pH7.4, 0.5% BSA, 0.015% ProClin™ 300, 25% glycerol

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20º C or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide derived between 198-274 amino acids of human PDX1

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Pancreatic And Duodenal Homeobox 1,Gsf,Idx-1,Ipf1,Iuf1,Mody4,Pagen1,Pdx-1,Stf-1,Pdx1

Cellular Localization

Cytoplasm,Cytosol,Nucleus

Background

The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (IDDM), as well as maturity onset diabetes of the young type 4 (MODY4). [provided by RefSeq, Aug 2017]

Database

Research Area

DATA IMAGES
GTX37568_20190129_IHC-P_19012901_251.jpg

GTX37568 IHC-P Image

IHC-P analysis of rat pancreas tissue using GTX37568 PDX1 antibody.

Package List Price ($)
$ 399