GeneTex
United States (US)

PDZK3 antibody [N1], N-term

GTX107989_WB_19011507_237.jpg

Cat No. GTX107989

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:3000
Not tested in other applications.

Calculated MW

302 kDa. ( Note )

Positive Control

A549

Predict Reactivity

Mouse, Rat(>80% identity)
PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1mg/ml

Antigen Species

Human

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human PDZK3. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

AIPC antibody, KIAA0300 antibody, PAPIN antibody, PDZK3 antibody, PIN1 antibody, PDZD2 antibody, PDZ domain containing 3 antibody, PDZ domain-containing protein 3 antibody, activated in prostate cancer protein antibody, PDZ domain-containing protein 2 antibody, PDZ domain containing 2 antibody

Cellular Localization

Nucleus (By similarity) , Cytoplasm , Endoplasmic reticulum , Processed PDZ domain-containing protein 2: Secreted

Background

Proteins containing PDZ domains have been shown frequently to bind the C-termini of transmembrane receptors or ion channels. They have also been shown to bind to other PDZ domain proteins and could possibly be involved in intracellular signalling. The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis. [provided by RefSeq]
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Database

Research Area

DATA IMAGES
GTX107989_WB_19011507_237.jpg

GTX107989 WB Image

Sample (30 ug of whole cell lysate)
A: A549 5% SDS PAGE
GTX107989 diluted at 1:1000

SDS
Glycerol.pdf
Thimerosal.pdf