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PEAR1 antibody

Anti-PEAR1 antibody used in IHC (Paraffin sections) (IHC-P). GTX85138
Anti-PEAR1 antibody used in Western Blot (WB). GTX85138
Anti-PEAR1 antibody used in IHC (Paraffin sections) (IHC-P). GTX85138

Cat. No. GTX85138

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all PEAR1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 μg/mL
IHC-P 2.5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

111 kDa. ( Note )

Positive Control

Rat Kidney Tissue Lysate(GTX27944) , Human Kidney Tissue Slide

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

PEAR1 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human PEAR1.The immunogen is located within the last 50 amino acids of PEAR1.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

platelet endothelial aggregation receptor 1 , JEDI , MEGF12

Cellular Localization

Cell membrane

Background

Platelet endothelial aggregation receptor 1 (PEAR1) is a platelet receptor that signals upon the formation of platelet-platelet contacts independent of platelet activation and secondary to platelet aggregation. Upon platelet aggregation stimulated by physiological agonists, PEAR1 becomes tyrosine- and serine-phosphorylated; the tyrosine phosphorylation can be inhibited by eptifibatide, an aIIbb3 antagonist that also inhibits platelet aggregation. Recent studies have indicated that genetic variations in PEAR1, may be associated with enhanced agonist-induced platelet aggregation.

Database

Research Area

DATA IMAGES

Anti-PEAR1 antibody used in IHC (Paraffin sections) (IHC-P). GTX85138

GTX85138 IHC-P Image

IHC-P analysis of human kidney tissue using GTX85138 PEAR1 antibody.
Working concentration : 20 μg/ml

Anti-PEAR1 antibody used in Western Blot (WB). GTX85138

GTX85138 WB Image

WB analysis of rat kidney tissue lysate in (A) the absence and (B) the presence of blocking peptide using GTX85138 PEAR1 antibody.
Working concentration : 1 μg/ml

Anti-PEAR1 antibody used in IHC (Paraffin sections) (IHC-P). GTX85138

GTX85138 IHC-P Image

IHC-P analysis of human kidney tissue using GTX85138 PEAR1 antibody.
Working concentration : 2.5 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399