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PEG3 antibody

Anti-PEG3 antibody used in IHC (Paraffin sections) (IHC-P). GTX37357

Cat. No. GTX37357

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human, Rat
Package
100 μg ($399)
See all PEG3 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:400-800
Not tested in other applications.

Calculated MW

181 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM TBS, 0.5% BSA, 25% Glycerol

Preservative

0.015% ProClin 300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide derived between 1511-1578 amino acids of human PEG3

Purification

Protein A purified

Conjugation

Unconjugated

RRID

AB_11166557

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

paternally expressed 3 , PW1 , ZKSCAN22 , ZNF904 , ZSCAN24

Cellular Localization

Nucleus,Cytoplasm

Background

In human, ZIM2 and PEG3 are treated as two distinct genes though they share multiple 5' exons and a common promoter and both genes are paternally expressed (PMID:15203203). Alternative splicing events connect their shared 5' exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3. In contrast, in other mammals ZIM2 does not undergo imprinting and, in mouse, cow, and likely other mammals as well, the ZIM2 and PEG3 genes do not share exons. Human PEG3 protein belongs to the Kruppel C2H2-type zinc finger protein family. PEG3 may play a role in cell proliferation and p53-mediated apoptosis. PEG3 has also shown tumor suppressor activity and tumorigenesis in glioma and ovarian cells. Alternative splicing of this PEG3 gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Sep 2009]

Database

Research Area

DATA IMAGES

Anti-PEG3 antibody used in IHC (Paraffin sections) (IHC-P). GTX37357

GTX37357 IHC-P Image

IHC-P analysis of rat brain tissue using GTX37357 PEG3 antibody.

REFERENCE

Application Reference

Cao C et al. J Genet Genomics 2020; HPV-CCDC106 integration alters local chromosome architecture and hijacks an enhancer by three-dimensional genome structure remodeling in cervical cancer.
Application : IHC-P
Reactivity : Human
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SDS
Glycerol.pdf
Proclin.pdf
Package List Price ($)
$ 399