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PER2 (phospho Ser662) antibody

Anti-PER2 (phospho Ser662) antibody used in Western Blot (WB). GTX55438
Anti-PER2 (phospho Ser662) antibody used in Western Blot (WB). GTX55438
Anti-PER2 (phospho Ser662) antibody used in IHC (Paraffin sections) (IHC-P). GTX55438

Cat. No. GTX55438

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse
Package
100 μl ($399)
See all PER2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:3000
IHC-P 1:50-1:100
Not tested in other applications.

Calculated MW

137 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS (without Mg²⁺ and Ca²⁺) pH7.4, 150mM NaCl, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide sequence around phosphorylation site of serine 662 (A-E-S(p)-V-A) derived from human PER2.

Purification

Purified by antigen-affinity chromatography. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

period circadian regulator 2 , FASPS , FASPS1

Cellular Localization

Cytoplasm

Background

This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene may increase the risk of getting certain cancers and have been linked to sleep disorders. [provided by RefSeq, Jan 2014]

Database

Research Area

DATA IMAGES

Anti-PER2 (phospho Ser662) antibody used in Western Blot (WB). GTX55438

GTX55438 WB Image

WB analysis of extracts from 3T3, HeLa, and K562 cells using GTX55438 PER2 (phospho Ser662) antibody.
Left : Primary antibody pre-incubated with the antigen specific peptide
Right : Primary antibody

Anti-PER2 (phospho Ser662) antibody used in Western Blot (WB). GTX55438

GTX55438 WB Image

WB analysis of extracts from 3T3 cells treated with PMA (125ng/ml 30mins) using GTX55438 PER2 (phospho Ser662) antibody.
Left : Primary antibody
Right : Primary antibody pre-incubated with the antigen specific peptide

Anti-PER2 (phospho Ser662) antibody used in IHC (Paraffin sections) (IHC-P). GTX55438

GTX55438 IHC-P Image

IHC-P analysis of human brain tissue using GTX55438 PER2 (phospho Ser662) antibody.
Left : Primary antibody
Right : Primary antibody pre-incubated with the antigen specific peptide

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399