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PEVR1 antibody

Anti-PEVR1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX87976
Anti-PEVR1 antibody used in Western Blot (WB). GTX87976

Cat. No. GTX87976

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF

Reactivity

 Human
Package
100 μg ($419)
See all PEVR1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500~1:1000
ICC/IF 1:100~1:500
Not tested in other applications.

Calculated MW

46 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 150mM NaCl, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human PEVR1 (43-92).

Purification

Purified by antigen-affinity chromatography
From serum

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

BVVLS2 , D15Ertd747e , GPCR41 , GPR172A , PAR1 , RFT3 , RFVT2 , SLC52A2 , hRFT3 , solute carrier family 52 member 2 , PEVR1 , solute carrier family 52 (riboflavin transporter), member 2

Cellular Localization

Cell membrane

Background

This gene encodes a membrane protein which belongs to the riboflavin transporter family. In humans, riboflavin must be obtained by intestinal absorption because it cannot be synthesized by the body. The water-soluble vitamin riboflavin is processed to the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) which then act as intermediaries in many cellular metabolic reactions. Paralogous members of the riboflavin transporter gene family are located on chromosomes 17 and 20. Unlike other members of this family, this gene has higher expression in brain tissue than small intestine. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. Mutations in this gene have been associated with Brown-Vialetto-Van Laere syndrome 2 - an autosomal recessive progressive neurologic disorder characterized by deafness, bulbar dysfunction, and axial and limb hypotonia. [provided by RefSeq, Jul 2012]

Database

Research Area

DATA IMAGES

Anti-PEVR1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX87976

GTX87976 ICC/IF Image

ICC/IF analysis of MCF7 cells using GTX87976 PEVR1 antibody. The picture on the right is blocked with the synthesized peptide.

Anti-PEVR1 antibody used in Western Blot (WB). GTX87976

GTX87976 WB Image

WB analysis of A549 cell lysates using GTX87976 PEVR1 antibody. The lane on the right is blocked with the synthesized peptide.

REFERENCE

Application Reference

Alessia Niceforo et al. Dis Model Mech 2021; Altered cytoskeletal arrangement in induced pluripotent stem cells (iPSCs) and motor neurons from patients with riboflavin transporter deficiency.
Application : ICC/IF
Reactivity : Human
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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 419