APPLICATION
Product Note
The peptide was used in the production of GTX89046.
PROPERTIES
Form
Lyophilized powder
Buffer
Reconstitute with 200μl distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O.
Preservative
No preservative
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Region/Sequence
C-DGLFDDSEDESDK
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
Pparg Coactivator 1 Alpha , Lem6 , Pgc-1(Alpha) , Pgc-1Alpha , Pgc-1V , Pgc1 , Pgc1A , Ppargc1 , Ppargc1A
Background
The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. [provided by RefSeq, Jul 2008]
Research Area
REFERENCE
There are currently no references for PGC1 alpha blocking peptide (GTX89046-PEP). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for PGC1 alpha blocking peptide (GTX89046-PEP). Be the first to share your experience with this product.