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PGCC1 antibody

Anti-PGCC1 antibody used in Western Blot (WB). GTX85254

Cat. No. GTX85254

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all PGCC1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.5 - 1 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

104 kDa. ( Note )

Positive Control

Rat Thymus Tissue Lysate(GTX24041)

Product Note

This antibody will not cross-react with FAM120A.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

PGCC1 antibody was raised against an 18 amino acid synthetic peptide from near the carboxy terminus of human PGCC1.The immunogen is located within the last 50 amino acids of PGCC1.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

family with sequence similarity 120B , CCPG , KIAA1838 , PGCC1 , dJ894D12.1

Cellular Localization

Nucleus

Background

The transcription factor peroxisome proliferator-activated receptor gamma (PPARg) plays essential roles in adipogenesis by regulating adipocyte-specific genes through association of various co-factors. One such co-factor, PGCC1 (also known as FAM120B), is widely expressed in adult tissues and throughout embryonic development. Overexpression of this protein in OP9 pre-adipocytes promoted their differentiation into adipocytes, and knockdown of PGCC1 expression through RNA interference blocked this process. PGCC1 is homologous to C9orf10 (also known as FAM120A) and has been mapped to chromosome Xp11.22. At least two isoforms of PGCC1 are known to exist. This antibody will not cross-react with FAM120A.

Database

Research Area

DATA IMAGES

Anti-PGCC1 antibody used in Western Blot (WB). GTX85254

GTX85254 WB Image

WB analysis of rat thymus tissue lysate using GTX85254 PGCC1 antibody.
Working concentration : (A) 0.5 and (B) 1 μg/ml

REFERENCE

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399