GeneTex
United States (US)

PHGDH antibody

GTX64499_20180530_IHC-P_18121411_578.jpg
GTX64499_20180530_WB_18121411_917.jpg
GTX64499_20180530_IHC-P_1_18121411_220.jpg

Cat No. GTX64499

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

57 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant funsion protein containing a sequence corresponding to amino acids 264-533 of human PHGDH (NP_006614.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

PGD Antibody , 3PGDH Antibody , PGDH Antibody , PGAD Antibody , PDG Antibody , SERA Antibody

Background

This gene encodes the enzyme which is involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptoms. Multiple alternatively spliced transcript variants have been found, however the full-length nature of most are not known. [provided by RefSeq, Aug 2011]

Database

Research Area

DATA IMAGES
GTX64499_20180530_IHC-P_18121411_578.jpg

GTX64499 IHC-P Image

IHC-P analysis of rat brain tissue using GTX64499 PHGDH antibody.
Dilution : 1:100

GTX64499_20180530_WB_18121411_917.jpg

GTX64499 WB Image

WB analysis of various samples using GTX64499 PHGDH antibody.
Dilution : 1:1000
Loading : 25μg per lane

GTX64499_20180530_IHC-P_1_18121411_220.jpg

GTX64499 IHC-P Image

IHC-P analysis of rat lung tissue using GTX64499 PHGDH antibody.
Dilution : 1:100

Package List Price ($)
$ 319