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PHOX2A antibody

Anti-PHOX2A antibody used in IHC (Paraffin sections) (IHC-P). GTX17170
Anti-PHOX2A antibody used in Western Blot (WB). GTX17170
Anti-PHOX2A antibody used in IHC (Paraffin sections) (IHC-P). GTX17170

Cat. No. GTX17170

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all PHOX2A products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 μg/mL
IHC-P 2.5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

30 kDa. ( Note )

Positive Control

Human Brain Tissue Slide(GTX22203) , Rat Brain Tissue Lysate(GTX27942)

Product Note

PHOX2A antibody is predicted to not cross-react with other paired homeobox family members.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

PHOX2A antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human PHOX2A.The immunogen is located within the last 50 amino acids of PHOX2A.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

paired like homeobox 2A , ARIX , CFEOM2 , FEOM2 , NCAM2 , PMX2A

Cellular Localization

Nucleus

Background

The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-PHOX2A antibody used in IHC (Paraffin sections) (IHC-P). GTX17170

GTX17170 IHC-P Image

IHC-P analysis of human brain tissue using GTX17170 PHOX2A antibody.
Working concentration : 20 μg/ml

Anti-PHOX2A antibody used in Western Blot (WB). GTX17170

GTX17170 WB Image

WB analysis of rat brain tissue lysate in (A) the absence and (B) the presence of blocking peptide using GTX17170 PHOX2A antibody.
Working concentration : 1 μg/ml

Anti-PHOX2A antibody used in IHC (Paraffin sections) (IHC-P). GTX17170

GTX17170 IHC-P Image

IHC-P analysis of human brain tissue using GTX17170 PHOX2A antibody.
Working concentration : 2.5 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399