GeneTex
United States (US)

PI3 kinase p101 antibody [C2C3-2], C-term

Genetex PI 3 Kinase 813 1 in 15000 400X 2.2011_19011720_269.jpg
GTX107813_40009_20160720_IHC-P_R_19011507_813.jpg

Cat No. GTX107813

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application IHC-P
Reactivity Human, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 1:100-1:1000
Not tested in other applications.

Calculated MW

97 kDa. ( Note )

Positive Control

FFPE normal human esophagus

Predict Reactivity

Mouse, Chicken, Pig(>80% identity)
PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.99 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human PI3 kinase p101. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Phosphoinositide-3-Kinase Regulatory Subunit 5,F730038I15Rik,Foap-2,P101-Pi3K,P101,Pik3R5

Cellular Localization

Nucleus , Cytoplasm , Membrane; Peripheral membrane protein

Background

Receptor-regulated class I phosphoinositide 3-kinases (PI3Ks) phosphorylate the membrane lipid phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) to PtdIns(3,4,5)P3, which in turn recruits and activates cytosolic effectors involved in proliferation, survival, or chemotaxis. PIK3R5 is a PI3K regulatory subunit (Brock et al., 2003 [PubMed 12507995]).[supplied by OMIM]

Database

DATA IMAGES
Genetex PI 3 Kinase 813 1 in 15000 400X 2.2011_19011720_269.jpg

GTX107813 IHC-P Image

Immunohistochemical staining of FFPE normal human esophagus using anti-PI3K p101 antibody (GTX107813). Nuclei are counterstained with methyl green.

GTX107813_40009_20160720_IHC-P_R_19011507_813.jpg

GTX107813 IHC-P Image

PI3 kinase p101 antibody [C2C3-2], C-term detects PI3 kinase p101 protein at cytoplasm in rat brain by immunohistochemical analysis.
Sample: Paraffin-embedded rat brain.
PI3 kinase p101 antibody [C2C3-2], C-term (GTX107813) diluted at 1:250.

Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 319
$ 169