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PI3 kinase p85 alpha antibody [8-2D-4D]

Cat. No. GTX23132

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 8-2D-4D

Isotype

 IgG1

Application

 WB, ICC/IF

Reactivity

 Human, Mouse, Rat
Package
500 μl ($399)
See all PI3 kinase p85 alpha products

APPLICATION

Application Note

For IF: Use at an assay dependent dilution. For WB: Use at an assay dependent dilution. Detects a band of ~ 85 kDa, which corresponds to the predicted molecular weight of PI 3 Kinase. Optimal dilutions/concentrations should be determined by the researcher.

Calculated MW

84 kDa. ( Note )

Positive Control

Jurkat or A431 cells

PROPERTIES

Form

Liquid

Buffer

PBS, 0.2% BSA

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Purified fragment (aa 333 - 430) of recombinant human PI-3-K p85 alpha subunit.

Purification

Protein G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

phosphoinositide-3-kinase regulatory subunit 1 , AGM7 , GRB1 , IMD36 , p85 , p85-ALPHA

Background

Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011]

Database

Research Area

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399