GeneTex
United States (US)

PINK1 antibody

GTX31581_2766_WB_20180221_18121410_917.jpg
GTX31581_1219_IHC-P_20180221_18121410_689.jpg
GTX31581_1220_IHC-P_20180221_18121410_497.jpg
GTX31581_2767_WB_20180221_18121410_331.jpg

Cat No. GTX31581

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, ELISA
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 - 2 μg/mL
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

63 kDa. ( Note )

Positive Control

A431 Cell Lysate(GTX27909) , Mouse Spleen Tissue Lysate(GTX27937) , Rat Spleen Tissue Lysate(GTX27945)

Specificity/Sensitivity

At least two isoforms are known to exist; this antibody will only detect the longer isoform. PINK1 antibody will detect the cleaved and uncleaved form of PINK1.
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

PINK1 antibody was raised against a 16 amino acid peptide near the amino terminus of human PINK1.The immunogen is located within amino acids 120 - 170 of PINK1.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Pten Induced Putative Kinase 1,Brpk,Park6,Pink1

Background

This gene encodes a serine/threonine protein kinase that localizes to mitochondria. It is thought to protect cells from stress-induced mitochondrial dysfunction. Mutations in this gene cause one form of autosomal recessive early-onset Parkinson disease. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX31581_2766_WB_20180221_18121410_917.jpg

GTX31581 WB Image

WB analysis of (A) mouse and (B) rat spleen tissue lysate using GTX31581 PINK1 antibody.
Working concentration : 1 μg/ml

GTX31581_1219_IHC-P_20180221_18121410_689.jpg

GTX31581 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX31581 PINK1 antibody.
Working concentration : 5 μg/ml

GTX31581_1220_IHC-P_20180221_18121410_497.jpg

GTX31581 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX31581 PINK1 antibody.
Working concentration : 20 μg/ml
Green : Primary antibody
Blue : DAPI
Red : Actin

GTX31581_2767_WB_20180221_18121410_331.jpg

GTX31581 WB Image

WB analysis of A431 cell lysate in (A) the absence and (B) the presence of blocking peptide using GTX31581 PINK1 antibody.
Working concentration : 1 μg/ml

Package List Price ($)
$ 339