PKC delta (phospho Ser645) antibody

Cat. No. GTX25657

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, IHC-P
Reactivity	Human
Package	50 μl ($399)

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Datasheet

View product citations for antibody GTX25657 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
WB	1:500 - 1:1000
IHC-P	1:50 - 1:100

Not tested in other applications.

Calculated MW

78 kDa. ( Note )

Predict Reactivity

Mouse, Rat(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS (without Mg²⁺ and Ca²⁺) pH7.4, 150mM NaCl, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized phosphopeptide derived from human PKCδ around the phosphorylation site of serine 645 (R-L-Sp-Y-S).

Purification

Purified by sequential chromatography on phospho- and non-phospho-peptide affinity columns.
From serum

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

ALPS3,CVID9,MAY1,PKCD,PRKCD,nPKCdelta,protein kinase C delta,PKC delta

Cellular Localization

Cytoplasm,Perinuclear region,Nucleus,Cell membrane

Background

The protein encoded by this gene is a member of the protein kinase C family of serine- and threonine-specific protein kinases. The encoded protein is activated by diacylglycerol and is both a tumor suppressor and a positive regulator of cell cycle progression. Also, this protein can positively or negatively regulate apoptosis. Defects in this gene are a cause of autoimmune lymphoproliferative syndrome. [provided by RefSeq, Aug 2017]

Database

Gene ID: 5580 PRKCD
UniProt: Q05655 PRKCD

Research Area

DATA IMAGES

GTX25657 IHC-P Image

IHC-P analysis of human breast carcinoma tissue using GTX25657 PKC delta (phospho Ser645) antibody.

GTX25657 WB Image

WB analysis of MCF7 cell lysate using GTX25657 PKC delta (phospho Ser645) antibody (Lane 3 and 4) and PKCδ antibody (Lane 1 and 2).

REFERENCE

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REVIEW

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Package

List Price ($)

50 μl

$ 399

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