APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:500 - 1:2000 |
| 1:50 - 1:200 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS, 50% Glycerol
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 488-737 of human PRKCE (NP_005391.1).
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
protein kinase C epsilon , PKCE , nPKC-epsilon
Cellular Localization
Cytoplasm,Cytoplasm, cytoskeleton,Cell membrane,Nucleus
Background
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX55749 IHC-P Image
IHC-P analysis of rat spleen tissue using GTX55749 PKC epsilon antibody.
Dilution : 1:200
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GTX55749 IHC-P Image
IHC-P analysis of human stomach tissue using GTX55749 PKC epsilon antibody.
Dilution : 1:100
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GTX55749 IHC-P Image
IHC-P analysis of human esophageal cancer tissue using GTX55749 PKC epsilon antibody.
Dilution : 1:200
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GTX55749 WB Image
WB analysis of various sample lysates using GTX55749 PKC epsilon antibody.
Dilution : 1:500
Loading : 25μg per lane
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REFERENCE
There are currently no references for PKC epsilon antibody (GTX55749). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for PKC epsilon antibody (GTX55749). Be the first to share your experience with this product.
