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PKC mu (phospho Ser738 / Ser742) antibody

Anti-PKC mu (phospho Ser738 / Ser742) antibody used in Western Blot (WB). GTX52343

Cat No. GTX52343

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC

Reactivity

Human, Mouse, Rat
Package
100 μg ($319)

APPLICATION

Application Note

WB 1:500-1:2000, IHC 1:50-1:200

Calculated MW

102 kDa. ( Note )

Specificity/Sensitivity

Based on sequence homology, this antibody may cross with other family members such as PRKD2 , PRKD3 proteins when phosphorylated at the equivalent sites.

PROPERTIES

Form

Liquid

Buffer

phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthesized peptide derived from human PKC mu around the phosphorylation site of Ser738/Ser742.

Purification

Antigen affinity purification

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Protein Kinase D1 , Chded , Pkc-Mu , Pkcm , Pkd , Prkcm , Prkd1

Background

PRKD1 is a serine/threonine kinase that regulates a variety of cellular functions, including membrane receptor signaling, transport at the Golgi, protection from oxidative stress at the mitochondria, gene transcription, and regulation of cell shape, motility, and adhesion (summary by Eiseler et al., 2009 [PubMed 19329994]).[supplied by OMIM, Nov 2010]

Database

Research Area

DATA IMAGES

Anti-PKC mu (phospho Ser738 / Ser742) antibody used in Western Blot (WB). GTX52343

GTX52343 WB Image

Western blot analysis of PKC mu phosphorylation expression in PMA treated A549 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.

REFERENCE

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REVIEW

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SDS
Glycerol.pdf
Sodium Azide.pdf