GeneTex
United States (US)

PKN1 antibody

GTX64829_20180530_IHC-P_1_18121411_960.jpg
GTX64829_20180530_WB_18121411_672.jpg
GTX64829_20180530_IHC-P_18121411_884.jpg
GTX64829_20180530_IHC-P_2_18121411_838.jpg

Cat No. GTX64829

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:1000
IHC-P 1:50 - 1:100
Not tested in other applications.

Calculated MW

104 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant funsion protein containing a sequence corresponding to amino acids 1-300 of human PKN1 (NP_002732.3).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

PRK1 Antibody , PKN ALPHA Antibody , DBK Antibody , PRKCL1 Antibody , PKN Antibody , PAK1 Antibody

Background

The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX64829_20180530_IHC-P_1_18121411_960.jpg

GTX64829 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX64829 PKN1 antibody.
Dilution : 1:100

GTX64829_20180530_WB_18121411_672.jpg

GTX64829 WB Image

WB analysis of various samples using GTX64829 PKN1 antibody.
Dilution : 1:1000
Loading : 25μg per lane

GTX64829_20180530_IHC-P_18121411_884.jpg

GTX64829 IHC-P Image

IHC-P analysis of human lung tissue using GTX64829 PKN1 antibody.
Dilution : 1:100

GTX64829_20180530_IHC-P_2_18121411_838.jpg

GTX64829 IHC-P Image

IHC-P analysis of mouse lung tissue using GTX64829 PKN1 antibody.
Dilution : 1:100

Package List Price ($)
$ 319