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PLA2G4A antibody

Anti-PLA2G4A antibody used in IHC (Paraffin sections) (IHC-P). GTX66631
Anti-PLA2G4A antibody used in Western Blot (WB). GTX66631
Anti-PLA2G4A antibody used in Western Blot (WB). GTX66631

Cat No. GTX66631

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human, Mouse, Rat
Package
100 μl ($349)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:1000
IHC-P 1:50-1:200
Not tested in other applications.

Calculated MW

85 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS pH7.2, 0.05% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide, corresponding to amino acids 480-530 of Human c-PLA2.

Purification

Purified by antigen-affinity chromatography
From serum

Purity

> 95% (by SDS-PAGE)

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

phospholipase A2 group IVA , PLA2G4 , cPLA2 , cPLA2-alpha

Cellular Localization

Cytoplasm,Cytoplasmic vesicle

Background

This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]

Database

Research Area

DATA IMAGES

Anti-PLA2G4A antibody used in IHC (Paraffin sections) (IHC-P). GTX66631

GTX66631 IHC-P Image

IHC-P analysis of human breast carcinoma tissue using GTX66631 PLA2G4A antibody.
Dilution : 1:100

Anti-PLA2G4A antibody used in Western Blot (WB). GTX66631

GTX66631 WB Image

WB analysis of various samples using GTX66631 PLA2G4A antibody.
Lane1 : THP-1 whole cell lysate(40ug)
Lane2 : MEF whole cell lysate(10ug)
Lane3 : H9C2 whole cell lysate(40ug)
Lane4 : K562 whole cell lysate(10ug)
Lane5 : Jurkat whole cell lysate(40ug)
Dilution : 1:500

Anti-PLA2G4A antibody used in Western Blot (WB). GTX66631

GTX66631 WB Image

WB analysis of various samples using GTX66631 PLA2G4A antibody.
Lane1 : A549 whole cell lysate(40μg)
Lane2 : BV2 whole cell lysate(15μg)
Dilution : 1:500

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 349